A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GENERIC NAME  
Warfarin Anticoagulation in Neuraxial Blockade
Warfarin Dosage and INR Form  
Wound Care Products P&T
  • Accuzyme and Ethezyme 830 are equivalent products containing identical amounts of active ingredients. Pharmacy will stock and autosubstitute the most cost effective product.
  • Panafil and Ziox Ointment are equivalent products containing identical amounts of active ingredients. Pharmacy will stock and autosubstitute the most cost effective product.

 

 

Accuzyme Ointment

Ethezyme 830 Ointment

Panafil Ointment

Ziox Ointment

Santyl Ointment

Xenaderm

Indications

Debridement of necrotic tissue and liquefaction of slough in acute and chronic lesions such as pressure ulcers, varicose and diabetic ulcers, burns, postoperative wounds, pilonidal cyst wounds, carbuncles and miscellaneous traumatic or infected wounds.

Acute and chronic lesions such as varicose, diabetic and decubitus ulcers, burns, postoperative wounds, pilonidal cyst wounds, carbuncles and miscellaneous traumatic of infected wounds.

Debriding chronic dermal ulcers.

Promote healing and the treatment of decubitus ulcers, varicose ulcers and dehiscent wounds.

Dosing Frequency

Once or twice daily

Once or twice daily

One daily

> Twice daily

Ingredients

Papain 8.3 x 105 units/gram

100 mg Urea/ gram

Hydrophilic ointment base

Papain 8.3 x 105 units/gram

100 mg Urea/ gram

Hydrophilic ointment base

Papain 5.2 x 105 /gram,

100 mg/gram Urea,

0.5% Chlorophyllin Copper Complex

in a hydrophilic base

Collagenase 250 units/gram

White petrolatum USP

Trypsin 90 units/gram,

Balsam Peru 87 mg/gram,

Castor Oil 788 mg/gram

Action

Papain digest nonviable protein.

 

Urea denatures nonviable protein making is susceptible to enzymatic digestion and exposes sulfhydryl groups which active papain.

Papain digest nonviable protein.

 

Urea denatures nonviable protein making is susceptible to enzymatic digestion and exposes sulfhydryl groups which active papain.

 

Chlorophyllin copper complex inhibits the hemagglutinating and inflammatory properties of protein degradation products in the wound.

 

Collagenase digest collagen in necrotic tissue

Balsam Peru is a capillary bed stimulant used to increase circulation in the wound site area. Castor oil is used to improve epithelialization by preventing drying and cornification and is a protective covering.  Trypsin is a debriding agent.

Active pH range

3-7

3-12

3-7

3-12

6-8

 

Inactivate by

Heavy metals, hydrogen peroxide

Heavy metals, hydrogen peroxide

Heavy metals

 

Cost per gram

$1.27

$0.43

$2.17

$0.98

$1.60

$0.65

 
Wound Care Products NOT carried by pharmacy
   
   

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